Population pharmacokinetics of FOLFIRINOX: a review of studies and parameters.
Laure DeymeDominique BarbolosiFlorence GattaccecaPublished in: Cancer chemotherapy and pharmacology (2018)
The current review allows for a global understanding of FOLFIRINOX pharmacokinetics, and will provide a basis for further development of pharmacokinetics-pharmacodynamics-toxicity models for model-driven FOLFIRINOX protocol optimization to reach the best benefit-to-risk ratio.