Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner.

Jinghai WuXin LiuJulie A Wallace ReeserAnthony J TrimboliThierry PécotGina M SizemoreShan K NaiduSoledad A FernandezLianbo YuMichael HallettMorag ParkGustavo W LeoneBlake E HildrethMichael C Ostrowski

Published in: Molecular cancer research : MCR (2022)

Expression of the p53 tumor suppressor in breast cancer tumor stroma regulates tumorigenesis in an oncogene-specific manner, influences the tumor immune landscape, and ultimately impacts patient survival.

Keyphrases

poor prognosis
single cell
free survival
bone marrow
case report