LncRNA 51325 Alleviates Bone Cancer Induced Hyperalgesia Through Inhibition of Pum2.

Yahui WangChengfei XuPeng LiuQiuli HeShihua ZhangZhihao LiuChaobo NiLiping ChenTong ZhiLongsheng XuLiang ChengXuewu LinMing YaoHuadong Ni

Published in: Journal of pain research (2024)

Our findings indicate that lncRNA51325 plays a role in regulating bone cancer pain by inhibiting Pum2 expression, offering a promising avenue for novel treatments targeting nociceptive hypersensitivity induced by bone metastatic cancer.

Keyphrases

papillary thyroid
squamous cell
bone mineral density
neuropathic pain
small cell lung cancer
long non coding rna
poor prognosis
lymph node metastasis
bone regeneration
bone loss
signaling pathway
pain management
childhood cancer
young adults
oxidative stress
spinal cord
mouse model
endothelial cells