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Transcriptional responses of Leishmania (Leishmania) amazonensis in the presence of trivalent sodium stibogluconate.

Luz H PatinoCarlos MuskusJuan David Ramírez
Published in: Parasites & vectors (2019)
This work identified global transcriptomic changes in an in vitro-adapted strain in response to SbIII. Our results provide relevant information to continue understanding the mechanism used by parasites of the subgenus Leishmania (L. amazonensis) to generate an antimony-resistant phenotype.
Keyphrases
  • gene expression
  • transcription factor
  • single cell
  • rna seq
  • health information
  • healthcare
  • oxidative stress
  • plasmodium falciparum