Broncho Vaxom (OM-85) modulates rhinovirus docking proteins on human airway epithelial cells via Erk1/2 mitogen activated protein kinase and cAMP.

Michael RothChristian PasqualiDaiana StolzMichael Tamm

Published in: PloS one (2017)

The OM-85-induced increased of C1q-R and β-defensin, both important for antigen presentation and phagocytosis, supports its activity in host cell's defence against Rhinovirus infection.

Keyphrases

endothelial cells
high glucose
protein kinase
single cell
signaling pathway
molecular dynamics
diabetic rats
cell therapy
molecular dynamics simulations
cell proliferation
induced pluripotent stem cells
pluripotent stem cells
pi k akt
binding protein
drug induced
protein protein
tyrosine kinase
oxidative stress