Critical PDT Theory VII: Preclinical Translation.
David KesselPublished in: Photochemistry and photobiology (2023)
The translation of photodynamic effects into clinical practice is a complex process that involves the pharmacokinetics of photosensitizing agents, light dosimetry and oxygenation levels. But een the 'translation' of basic photobiology into meaningful preclinical information can be challenging. Some thoughts on directions for progress in clinical trials are suggested.