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Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression.

Richard James CuthbertAbdulla WatadEvangelos M FragkakisRobert DunsmuirPeter LoughenburyAlmas KhanPeter A MillnerAdam DavisonHelena Marzo-OrtegaDarren NewtonCharles BridgewoodDennis G McGonagle
Published in: Annals of the rheumatic diseases (2019)
Spinal entheseal Vδ1 and Vδ2 subsets are tissue resident cells with inducible IL-17A production with evidence that the Vδ1 subset does so independently of IL-23R expression.
Keyphrases
  • poor prognosis
  • endothelial cells
  • induced apoptosis
  • patient safety
  • spinal cord
  • binding protein
  • cell cycle arrest
  • signaling pathway
  • oxidative stress
  • cell death
  • cell proliferation
  • rna seq
  • pi k akt