Human Inborn Errors of Immunity in Pyoderma Gangrenosum: A Systematic Review.

Yasmine OpreaDaniel R AntohiMorgan VagueCaroline Delbourgo PattonBenedict WuAlex G Ortega-Loayza

Published in: American journal of clinical dermatology (2024)

Human inborn errors of immunity may be implicated in the genetic predisposition to PG and may influence the clinical presentation. Due to the rarity of these diseases, further work must be done to describe the association between inborn errors of immunity and PG. Identifying inborn errors of immunity that may contribute to the development of PG may assist in further elucidating the mechanism of PG, guiding targeted treatment, and improving clinical outcomes for these patients.

Keyphrases

endothelial cells
patient safety
adverse drug
induced pluripotent stem cells
end stage renal disease
ejection fraction
pluripotent stem cells
newly diagnosed
prognostic factors
genome wide
dna methylation
copy number
quality improvement
drug induced
patient reported