Efficacy and safety of the GOLD FORCE multicentre randomized clinical trial: multielectrode phased radiofrequency vs. irrigated radiofrequency single-tip catheter with contact force ablation for treatment of symptomatic paroxysmal atrial fibrillation.
Lisette I S WintgensMartijn N KlaverMoniek MaarseStefan G SpitzerAnke LangbeinMartin J SwaansVincent F Van DijkJippe C BaltMaurits C E F WijffelsJan G P TijssenArif ElvanLucas V A BoersmaPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2022)
In this multicentre randomized clinical trial, ablation with ST-CF and PVAC Gold ablation catheters non-inferiority for efficacy was not met. AF recurrence was significantly more frequent in the PVAC Gold group compared to single-tip contact force group. Both groups had similarly low rates of adverse events. PVAC Gold ablation had significantly shorter procedure and ablation times.
Keyphrases
- catheter ablation
- atrial fibrillation
- left atrial
- left atrial appendage
- oral anticoagulants
- radiofrequency ablation
- double blind
- clinical trial
- single molecule
- heart failure
- silver nanoparticles
- study protocol
- cystic fibrosis
- percutaneous coronary intervention
- cross sectional
- coronary artery disease
- minimally invasive
- venous thromboembolism
- replacement therapy