Effect of local zoledronate delivery on osseointegration: a systematic review of preclinical studies.

Sergio Varela KellesarianShatha Subhi ALHarthiMunerah Saleh BinshabaibFawad Javed

Published in: Acta odontologica Scandinavica (2017)

Local ZOL delivery (coating or topical) seems to enhance osseointegration in animals; however, from a clinical perspective, further randomized control trials with long-term follow-up are needed in this regard.

Keyphrases

double blind
open label
placebo controlled
phase iii
clinical trial
cell therapy
stem cells
randomized controlled trial
study protocol