Moderate-intensity treadmill running relieves motion-induced post-traumatic osteoarthritis mice by up-regulating the expression of lncRNA H19.

Xuchang ZhouHong CaoMiao WangJun ZouWei Wu

Published in: Biomedical engineering online (2021)

High-intensity treadmill running can cause injury to the knee cartilage in C57BL/6 mice which leads to PTOA and a decrease of lncRNA H19 expression in cartilage. Moderate-intensity exercise can relieve PTOA and partially reverse lncRNA H19 expression.

Keyphrases

high intensity
poor prognosis
resistance training
long non coding rna
binding protein
long noncoding rna
total knee arthroplasty
rheumatoid arthritis
adipose tissue
metabolic syndrome
high glucose
diabetic rats
endothelial cells
skeletal muscle
stress induced