Combined Transarterial Chemoembolization and External Beam Radiotherapy in a Patient with Recurrent Huge Hepatocellular Carcinoma after Hepatic Resection.
Jesang YuJinhong JungSang Min YoonPublished in: Journal of liver cancer (2020)
The optimal treatment strategy for unresectable huge hepatocellular carcinoma (HCC) is yet to be established. Non-surgical monotherapy demonstrated insufficient oncologic outcomes in previously reported studies. To improve the clinical outcomes of unresectable huge HCC, combined locoregional treatments can be considered in selected cases. Here, we report a case of 58-year-old male patient who was treated with combined transarterial chemoembolization (TACE) and external beam radiotherapy for recurrent HCC after a previous hepatic resection. After combined TACE and radiotherapy for the intrahepatic lesion, two metastases were diagnosed in the pelvic bones and lung; each lesion was successfully treated with salvage radiotherapy. During the long-term follow-up period (around 8 years 7 months after combined TACE and radiotherapy for the recurrent huge HCC), no definite viable tumors were observed in any of the treated liver, bone, and lung lesions.
Keyphrases
- locally advanced
- early stage
- rectal cancer
- radiation therapy
- radiation induced
- liver metastases
- squamous cell carcinoma
- radiofrequency ablation
- case report
- randomized controlled trial
- combination therapy
- type diabetes
- metabolic syndrome
- bone mineral density
- adipose tissue
- study protocol
- robot assisted
- smoking cessation
- skeletal muscle
- insulin resistance
- weight loss