Dynamic contrast-enhanced CT for the assessment of tumour response in malignant pleural mesothelioma: a pilot study.
Eyjolfur GudmundssonZacariah LabbyChristopher M StrausWilliam F SensakovicFeng LiBuerkley RoseAlexandra CunliffeHedy L KindlerSamuel G ArmatoPublished in: European radiology (2018)
• CT-derived haemodynamic parameters show differing trends between malignant pleural mesothelioma patients on treatment and patients off treatment • Changes in haemodynamic parameters do not correlate with changes in tumour bulk as measured according to the modified RECIST protocol • Differing trends across the two patient groups indicate the potential sensitivity of DCE-CT to assess pharmacodynamic endpoints in the treatment of MPM.
Keyphrases
- end stage renal disease
- computed tomography
- ejection fraction
- newly diagnosed
- chronic kidney disease
- contrast enhanced
- randomized controlled trial
- prognostic factors
- image quality
- magnetic resonance imaging
- dual energy
- peritoneal dialysis
- combination therapy
- risk assessment
- positron emission tomography
- patient reported outcomes
- patient reported
- replacement therapy