Sub-acute effects of psilocybin on EEG correlates of neural plasticity in major depression: Relationship to symptoms.
Patrick D SkosnikJordan SloshowerHamideh Safi-AghdamSurbhi PathaniaShariful A SyedBrian PittmanDeepak C D'SouzaPublished in: Journal of psychopharmacology (Oxford, England) (2023)
The increased theta power observed represents evidence of sustained changes in the brain following psilocybin. Given the correlation with enhancement in depressive symptoms, changes in theta may represent an EEG biomarker of the sustained effects of psilocybin, and may shed light on potential mechanisms of psilocybin's antidepressant effect. Taken together, these results complement the emerging notion that psilocybin, and perhaps other psychedelics, can produce long-term alterations in neuroplasticity.
Keyphrases
- working memory
- resting state
- depressive symptoms
- functional connectivity
- transcranial magnetic stimulation
- liver failure
- major depressive disorder
- social support
- white matter
- sleep quality
- intensive care unit
- respiratory failure
- high frequency
- physical activity
- prefrontal cortex
- multiple sclerosis
- hepatitis b virus
- subarachnoid hemorrhage
- high density