Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis.

Getachew Tesfaye BeyeneShewit KalayouTahira RiazTone Tønjum

Published in: BMC microbiology (2017)

DprA interacts with proteins essential for Nm DNA recombination in transformation, pilus biogenesis, and other functions associated with the inner membrane. Inverse downregulation of Nm DprA and PilG expression in the corresponding mutants indicates a link between DNA processing and pilus biogenesis.

Keyphrases

circulating tumor
cell free
single molecule
photodynamic therapy
poor prognosis
escherichia coli
binding protein
nucleic acid
dna damage
cell proliferation
dna repair
signaling pathway
circulating tumor cells
wild type