Navigating Post-Operative Outcomes: A Comprehensive Reframing of an Original Graded Prognostic Assessment in Patients with Brain Metastases.
Maria GoldbergMichel Gustavo Mondragón-SotoLaura DieringerGhaith AltawalbehPaul PöserLea BaumgartBenedikt WiestlerBernhard MeyerPhilipp J JostAmir Kaywan AftahyPublished in: Cancers (2024)
The prognostic value of the original GPA was confirmed in our cohort of patients who underwent surgery for BM. The RTB was identified as a parameter of high prognostic significance and was incorporated into an updated "volumetric GPA". This score provides a novel tool for prognosis and clinical decision making in patients undergoing surgery. This method may be useful for stratification and patient selection for further treatment and in future clinical trials.
Keyphrases
- brain metastases
- minimally invasive
- patients undergoing
- clinical trial
- coronary artery bypass
- small cell lung cancer
- end stage renal disease
- newly diagnosed
- prognostic factors
- surgical site infection
- randomized controlled trial
- case report
- type diabetes
- metabolic syndrome
- current status
- insulin resistance
- adipose tissue
- open label
- replacement therapy
- smoking cessation
- phase ii
- double blind
- glycemic control
- phase iii