Intestinal microbiomics and hepatic metabolomics insights into the potential mechanisms of probiotic Bifidobacterium pseudolongum CCFM1253 preventing acute liver injury in mice.
Weiling GuoShumao CuiXin TangYongqiu YanFeifei XiongQiuxiang ZhangJianxin ZhaoBingyong MaoHao ZhangPublished in: Journal of the science of food and agriculture (2023)
Bifidobacterium pseudolongum CCFM1253 can effectively alleviate inflammatory response and oxidative stress, and regulate the intestinal microbiota composition and liver metabolism, and elevate the liver riboflavin content in LPS-treated mice. Therefore, B. pseudolongum CCFM1253 could serves as a potential probiotic to ameliorate the host health. © 2023 Society of Chemical Industry.
Keyphrases
- liver injury
- drug induced
- inflammatory response
- oxidative stress
- high fat diet induced
- human health
- healthcare
- liver failure
- public health
- lps induced
- lipopolysaccharide induced
- mass spectrometry
- mental health
- type diabetes
- bacillus subtilis
- dna damage
- risk assessment
- toll like receptor
- respiratory failure
- skeletal muscle
- ischemia reperfusion injury
- metabolic syndrome
- immune response
- lactic acid
- social media
- insulin resistance
- hepatitis b virus
- newly diagnosed
- climate change
- anti inflammatory