Sites of metastasis and association with clinical outcome in advanced stage cancer patients treated with immunotherapy.
Mehmet Asim BilenJulie M ShabtoDylan J MartiniYuan LiuColleen LewisHannah CollinsMehmet AkceHaydn KissickBradley C CarthonWalid L ShaibOlatunji B AleseConor E SteuerChristina WuDavid H LawsonRagini KudchadkarViraj A MasterBassel El-RayesSuresh S RamalingamTaofeek K OwonikokoR Donald HarveyPublished in: BMC cancer (2019)
Liver metastases may be a poor prognostic factor in patients receiving IO on phase 1 clinical trials. The presence of liver metastases may warrant consideration in updated prognostic models if these findings are validated in a larger prospective cohort.