Maternal diet supplementation with high-docosahexaenoic-acid canola oil, along with arachidonic acid, promotes immune system development in allergy-prone BALB/c mouse offspring at 3 weeks of age.

Dhruvesh PatelJaqueline MunhozSusan GorukSue TsaiCaroline RichardCatherine J Field

Published in: European journal of nutrition (2023)

Plant-based source of DHA in maternal diet resulted in higher ex vivo production of inflammatory cytokines by splenocytes due to change in their phenotype, and this can skew T cell towards Th1 response in a Th2-dominant BALB/c mouse.

Keyphrases

fatty acid
physical activity
birth weight
weight loss
pregnancy outcomes
high fat diet
body mass index
pregnant women
type diabetes
metabolic syndrome
weight gain
insulin resistance
skeletal muscle
cell wall