Emergence of phylogenetically diverse and fluoroquinolone resistant Salmonella Enteritidis as a cause of invasive nontyphoidal Salmonella disease in Ghana.
Cassandra AldrichHassan HartmanNicholas FeaseyMarie Anne ChattawayDenise DekkerHassan M Al-EmranLesley LarkinJacquelyn McCormickNimako SarpongSimon Le HelloYaw Adu-SarkodieUrsula PanznerSe Eun ParkJustin ImFlorian MarksJürgen MayTimothy J DallmanDaniel EibachPublished in: PLoS neglected tropical diseases (2019)
Extensive phylogenetic diversity is evident amongst iNTS disease-associated S. Enteritidis in Ghana. Antimicrobial resistance profiles differed by clade, highlighting the challenges of devising empirical sepsis guidelines. The detection of fluoroquinolone resistance in phyletically-related poultry and human isolates is of major concern and surveillance and control measures within the region's burgeoning poultry industry are required to protect a human population at high risk of iNTS disease.