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Circular RNA hsa_circ_0005939 Regulates UHRF1BP1L Expression by Targeting miR-4693-3p to Promote Colorectal Cancer Progression.

Hua GeYan YanHaomin WangJun BianZhilong DengXian SuKaiyuan LuoJianfeng Bin
Published in: Protein and peptide letters (2024)
Our findings indicated an oncogenic role of hsa_circ_0005939 in CRC, and it enhanced malignant phenotypes of CRC cells through miR-4693-3p/UHRF1BP1L axis. Our study may offer promising biomarkers and therapeutic targets for CRC.
Keyphrases
  • induced apoptosis
  • poor prognosis
  • cell cycle arrest
  • transcription factor
  • endoplasmic reticulum stress
  • signaling pathway