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A novel self-micro-emulsifying delivery system (SMEDS) formulation significantly improves the fasting absorption of EPA and DHA from a single dose of an omega-3 ethyl ester concentrate.

Yan QinHilde NyheimElse Marie HaramJoseph M MoritzSvein Olaf Hustvedt
Published in: Lipids in health and disease (2017)
PRF-021 is a novel SMEDS formulation of Omega-3-acid EE demonstrating a marked improvement in absorption of a single dose of EPA and DHA EE under fasted conditions. This allows adequate absorption of Omega-3 from the supplement without the requirement of a high-fat meal.
Keyphrases
  • drug delivery
  • fatty acid
  • insulin resistance
  • ionic liquid
  • skeletal muscle
  • weight loss