Transposition of the great arteries is a rare type of critical congenital heart disease (CCHD) which commonly presents in the neonatal period and requires early diagnosis and intervention if the infant is to witness his/her first birthday. Here, we report a case of an 8-week-old term male infant who presented with a 2-day history of cough, breathlessness and cyanosis. Echocardiography confirmed dextro-transposition of the great arteries (d-TGA) with patent ductus arteriosus (PDA) and patent foramen ovale (PFO). The infant succumbed to cardiogenic shock due to late presentation and no access to definitive surgical intervention.