Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer.

Ricardo Romão Nazário LeãoJoana Dias ApolónioDonghyun LeeArnaldo FigueiredoUri TaboriPedro Castelo-Branco

Published in: Journal of biomedical science (2018)

Herein, we reviewed the underlying mechanisms of hTERT regulation, their role in oncogenesis, and the potential clinical applications in telomerase-dependent cancers.

Keyphrases

endothelial cells
papillary thyroid
squamous cell
induced pluripotent stem cells
pluripotent stem cells
risk assessment
human health