Crushing and Splitting Direct-Acting Antivirals for Hepatitis C Virus Treatment: A Case Series and Literature Review.

Kristen Whelchel Autumn D Zuckerman David E KorenCaroline DerrickJeannette L Bouchard Cody A Chastain

Published in: Open forum infectious diseases (2021)

Limited data exist regarding the use of direct-acting antivirals (DAAs) for hepatitis C virus (HCV) in patients who are unable to swallow tablets. This case series describes HCV treatment in patients requiring tablet manipulation, providing evidence for safety and effectiveness of HCV DAA tablet manipulation.

Keyphrases

hepatitis c virus
human immunodeficiency virus
end stage renal disease
newly diagnosed
ejection fraction
randomized controlled trial
chronic kidney disease
systematic review
prognostic factors
electronic health record
big data
artificial intelligence