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Identifying effect modifiers of CAR-T cell therapeutic efficacy: a systematic review and individual patient data meta-analysis protocol.

Manoj M LaluNatasha KekreJoshua MontroyMaryam GhiasiKevin HayScott McCombRisini WeeratnaHarold AtkinsBrian HuttonAyel YahyaAshish MasurekarMohamad SobhDean A Fergusson
Published in: Systematic reviews (2023)
Identifying characteristics that may act as modifiers of CAR-T cell efficacy is of paramount importance and can help shape future clinical trials in the field. Results from this study will be submitted for publication in a peer-reviewed scientific journal, presented at relevant conferences and shared with relevant stakeholders.
Keyphrases
  • systematic review
  • clinical trial
  • randomized controlled trial
  • case report
  • electronic health record
  • meta analyses
  • current status
  • big data
  • machine learning
  • study protocol
  • deep learning