Astilbin lowers the effective caffeine dose for decreasing lipid accumulation via activating AMPK in high-fat diet-induced obese mice.

Licong YangYanping ZhuShusheng ZhongGuo-Dong Zheng

Published in: Journal of the science of food and agriculture (2020)

The results obtained in the present study indicate that astilbin may decrease the effective dose of caffeine needed for an anti-obesity effect and also suggest that it suppresses fat accumulation via the activation of AMPK. © 2020 Society of Chemical Industry.

Keyphrases

high fat diet induced
insulin resistance
skeletal muscle
signaling pathway
adipose tissue
metabolic syndrome
type diabetes
protein kinase
fatty acid
physical activity