Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis.

Amena KeshawarzRoby JoehanesJiantao MaGha Young LeeRicardo CosteiraPei-Chien TsaiOlatz M MasachsJordana T BellRory WilsonBarbara ThorandJuliane WinkelmannAnnette PetersJakob LinseisenMelanie WaldenbergerTerho LehtimäkiPashupati P MishraMika KähönenOlli RaitakariMika HelminenCarol A WangPhillip E MeltonRae-Chi HuangCraig E PennellTherese A O'SullivanCarolina Ochoa-RosalesTrudy VoortmanJoyce B J van MeursKristin L YoungMisa GraffYujie WangDouglas P KielCaren E SmithPaul F JacquesDaniel Levy

Published in: Epigenetics (2023)

We identified significant associations of many CpG sites with vitamin C and E intake, and our results suggest that vitamin C intake may be associated with systems development and the immune response.

Keyphrases

dna methylation
systematic review
immune response
genome wide
gene expression
weight gain
toll like receptor
randomized controlled trial
copy number
body mass index
meta analyses