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Downregulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression.

Nan XuJianyong ZhuoYiyuan ChenRenyi SuHuan ChenZhensheng ZhangZhengxing LianDi LuXuyong WeiShusen ZhengXiao XuShuai WangQiang Wei
Published in: British journal of cancer (2023)
Ac4C modification of myeloid cells enhanced the HCC immunotherapy by suppressing PDL1 expression.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • bone marrow
  • acute myeloid leukemia
  • signaling pathway
  • poor prognosis
  • cell death
  • oxidative stress