Multifunctional mRNA-Based CAR T Cells Display Promising Antitumor Activity Against Glioblastoma.
Hanna MeisterThomas LookPatrick RothNatalia Teresa JarzebskaUğur ŞahinSohyon LeeBenjamin D HaleBerend SnijderLuca RegliVidhya Madapusi RaviDieter Henrik HeilandCharles L SentmanMichael WellerTobias WeissPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
These data provide a robust rationale for future clinical studies with mRNA-based multifunctional CAR T cells to treat malignant brain tumors.