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Transcriptional analysis of Helicobacter pylori cytotoxic-associated gene-pathogenicity island in response to different pH levels and proton pump inhibitor exposure.

Fatemeh RezaeiMasoud AlebouyehSeyedeh Zohre MirbagheriAmir EbrahimiAbbas Rahimi ForoushaniSiavosh Salmanzadeh-Ahrabi
Published in: Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology (2023)
Our results showed that omeprazole could increase the expression of H. pylori cagA and cagL at acidic pH. Heterogeneity among the strains probably has an impact on the extent of their interplay with PPIs. Further studies are needed to establish this correlation.
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