Circulating plasma cells as a predictive biomarker in Multiple myeloma: an updated systematic review and meta-analysis.
Qun LiLisha AiLiping ZuoJunying LiFei ZhaoAoshuang XuBo ZhangLi CaiHan YanChunyan SunPublished in: Annals of medicine (2024)
Our meta-analysis confirmed that the increased number of CPCs had a negative impact on the PFS and OS of MM patients. Therefore, CPCs could be a promising prognostic biomarker that helps with risk stratification and disease monitoring.
Keyphrases
- systematic review
- end stage renal disease
- multiple myeloma
- induced apoptosis
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- randomized controlled trial
- meta analyses
- oxidative stress
- patient reported outcomes
- cell death
- signaling pathway
- endoplasmic reticulum stress
- pi k akt