Manual Acupuncture Suppresses the Expression of Proinflammatory Proteins Associated with the NLRP3 Inflammasome in the Hippocampus of SAMP8 Mice.

Ning DingJing JiangMenghan Lu Jiatong HuYiyuan XuXiaoxiao Liu Zhi-Gang Li

Published in: Evidence-based complementary and alternative medicine : eCAM (2017)

MA can improve the learning and memory capabilities of SAMP8 mice. The negative regulation of the NLRP3/Caspase-1 pathway in the hippocampus may be a possible mechanism of MA in the treatment of AD.

Keyphrases

nlrp inflammasome
high fat diet induced
poor prognosis
signaling pathway
cognitive impairment
cerebral ischemia
prefrontal cortex
type diabetes
metabolic syndrome
induced apoptosis
insulin resistance
combination therapy
endoplasmic reticulum stress