SHMT2 Drives the Progression of Colorectal Cancer by Regulating UHRF1 Expression.

Xi-Mao Cui Yanfen Cui Tao Du Xiao-Hua Jiang Chun Song Shun Zhang Chiye Ma Yun Liu Qing Ni Yuzhe Gao Guanghui Wang

Published in: Canadian journal of gastroenterology & hepatology (2022)

Taken together, our findings reveal that UHRF1 is a novel target gene of SHMT2, which can be used as a potential therapeutic strategy for CRC therapy.

Keyphrases

genome wide
poor prognosis
copy number
single cell
dna methylation
binding protein
genome wide identification
gene expression
bone marrow
replacement therapy