Diffuse Alveolar Hemorrhage in a Patient with Antisynthetase Syndrome.
D A Vargas-GutiérrezFabio Solis-JimenezK I Arias CallejasL Cano CruzR Zapata ArenasA O Acero LópezP Puente RodríguezS Velázquez de la PazPublished in: Case reports in rheumatology (2019)
An alveolar hemorrhage case is reported as the initial manifestation of antisynthetase syndrome in a 40-year-old man, who is admitted to the Emergency Department for diagnostic approach of chronic cough and progressive dyspnea. The diagnosis of the alveolar hemorrhage was based on the presence of acute respiratory failure, decrease in hemoglobin levels, and observation of macrophages filled with hemosiderin. The antisynthetase syndrome was classified through a tomographic image compatible with a nonspecific interstitial pneumonia, along with antibodies associated to myositis (PL-12 and Ro-52). The study protocol was completed with the result of a myopathic pattern showed in electromyography. This patient presented a good response to steroids and disease-modifying antirheumatic drug (DMARD).
Keyphrases
- respiratory failure
- case report
- emergency department
- extracorporeal membrane oxygenation
- mechanical ventilation
- study protocol
- randomized controlled trial
- drug induced
- deep learning
- machine learning
- systemic sclerosis
- acute respiratory distress syndrome
- low grade
- open label
- aortic dissection
- systemic lupus erythematosus
- interstitial lung disease