Stem cell sources from human biological waste material: a role for the umbilical cord and dental pulp stem cells for regenerative medicine.
Monalisa DasAlastair J SloanPublished in: Human cell (2023)
Stem cell research with biological waste material is an area that holds promise to revolutionize treatment modalities and clinical practice. The interest in surgical remnants is increasing with time as research on human embryonic stem cells remains controversial due to legal and ethical issues. Perhaps, these restrictions are the motivation for the use of alternative mesenchymal stem cell (MSC) sources in the regenerative field. Stem cells (SCs) of Umbilical Cord (UC) and Dental Pulp (DP) have almost similar biological characteristics to other MSCs and can differentiate into a number of cell lineages with enormous potential future prospects. A concise critical observation of UC-MSCs and DP-MSCs is presented here reviewing articles from the last two decades along with other stem cell sources from different biological waste materials.
Keyphrases
- stem cells
- umbilical cord
- mesenchymal stem cells
- cell therapy
- endothelial cells
- drinking water
- heavy metals
- bone marrow
- clinical practice
- embryonic stem cells
- sewage sludge
- current status
- induced pluripotent stem cells
- municipal solid waste
- risk assessment
- pluripotent stem cells
- single cell
- big data
- life cycle
- replacement therapy