Insulin-Mediated Substrate Use in Women With Different Phenotypes of PCOS: the Role of Androgens.

Flavia TosiMichela VillaniMatteo MigazziGiulia FaccinSabrina GarofaloTom FiersJean-Marc KaufmanEnzo BonoraPaolo Moghetti

Published in: The Journal of clinical endocrinology and metabolism (2021)

In women with PCOS, regardless of phenotype, insulin-mediated substrate use is impaired. This phenomenon is greater in individuals with the classic phenotype. Free testosterone plays an independent role in insulin action abnormalities in glucose and lipid metabolism.

Keyphrases

type diabetes
glycemic control
polycystic ovary syndrome
blood glucose
blood pressure
metabolic syndrome
fatty acid
structural basis
weight loss