Body weight-dependent and independent improvement in lipid metabolism after Roux-en-Y gastric bypass in ApoE*3Leiden.CETP mice.

Erika TarascoChristina N BoyleGiovanni PellegriniMyrtha ArnoldRegula SteinerThorsten HornemannDimitris NasiasDimitris KardassisLynda WhitingThomas A Lutz

Published in: International journal of obesity (2005) (2019)

RYGB surgery improves glucose metabolism and greatly ameliorates lipid metabolism in part in a body weight-dependent manner. Given that ApoE3L.CETP mice were extensively studied to describe the MetS, and given that RYGB improved ceramide after surgery, our data confirmed the usefulness of ApoE3L.CETP mice after RYGB in deciphering the metabolic improvements to treat the MetS.

Keyphrases

roux en y gastric bypass
body weight
weight loss
gastric bypass
obese patients
high fat diet induced
cognitive decline
high fat diet
bariatric surgery
minimally invasive
multidrug resistant
type diabetes
mouse model
fatty acid
acute coronary syndrome
big data
skeletal muscle
atrial fibrillation