Refinement and validation of infrared thermal imaging (IRT): a non-invasive technique to measure disease activity in a mouse model of rheumatoid arthritis.
Zeynab NosratiMarta BergamoCristina Rodríguez-RodríguezKatayoun SaatchiUrs O HäfeliPublished in: Arthritis research & therapy (2020)
IRT proved to be a valid and unbiased method to detect temperature changes and quantify the degree of inflammation in a rapid and reproducible manner in longitudinal preclinical drug efficacy studies.
Keyphrases
- disease activity
- rheumatoid arthritis
- mouse model
- systemic lupus erythematosus
- rheumatoid arthritis patients
- ankylosing spondylitis
- oxidative stress
- high resolution
- juvenile idiopathic arthritis
- interstitial lung disease
- case control
- cell therapy
- loop mediated isothermal amplification
- emergency department
- stem cells
- adverse drug
- mesenchymal stem cells
- drug induced
- bone marrow
- electronic health record