Insulin Resistance Predicts Cognitive Decline: An 11-Year Follow-up of a Nationally Representative Adult Population Sample.

Laura L EkbladJuha O RinnePauli PuukkaHanna LaineSatu AhtiluotoRaimo SulkavaMatti ViitanenAntti Jula

Published in: Diabetes care (2017)

Our results show that higher serum fasting insulin and insulin resistance predict poorer verbal fluency and a steeper decline in verbal fluency during 11 years in a representative sample of an adult population. Prevention and treatment of insulin resistance might help reduce cognitive decline later in life.

Keyphrases

cognitive decline
insulin resistance
mild cognitive impairment
type diabetes
adipose tissue
metabolic syndrome
high fat diet
skeletal muscle
polycystic ovary syndrome
working memory
glycemic control
high fat diet induced
cross sectional
combination therapy