Five-year effectiveness of short messaging service (SMS) for pre-diabetes.
Carlos King-Ho WongShing-Chung SiuKa-Wai WongYee Tak Esther YuCindy Lo Kuen LamPublished in: BMC research notes (2018)
After a mean 57-month follow-up, 19 (18.3%) were lost to follow-up after the RCT period. Progression to diabetes occurred in 20 and 16 patients among the intervention and control group respectively, with no significant between-group difference (8.06 and 7.31 cases per 100 person years, respectively; Hazard Ratio in the intervention group, 1.184; 95% confidence interval, 0.612 to 2.288; p-value = 0.616). No significant effect of SMS on reduction in diabetes was observed in overall and pre-defined subgroups. The SMS intervention preserved the clinical benefits within the trial period but failed to transform from treatment efficacy to long-term effectiveness beyond 2 years after intervention. Trail registration ClinicalTrials.gov Identifier NCT01556880, retrospectively registered on March 16, 2012.
Keyphrases
- randomized controlled trial
- type diabetes
- cardiovascular disease
- study protocol
- glycemic control
- end stage renal disease
- systematic review
- healthcare
- newly diagnosed
- chronic kidney disease
- mental health
- clinical trial
- peritoneal dialysis
- prognostic factors
- phase iii
- insulin resistance
- adipose tissue
- patient reported outcomes