Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.

Anthony Wing-Hung ChanGrace L H WongHoi-Yun ChanJoanna H M TongYau-Hei YuPaul C L ChoiHenry L Y ChanKa-Fai ToVincent W S Wong

Published in: Journal of gastroenterology and hepatology (2017)

Concurrent fatty liver is common in HBV-infected patients and an independent risk factor potentiating HBV-associated HCC development by 7.3-fold. The risk of HBV-related HCC is increased by APOC3 gene polymorphism, and further characterization is required by its role.

Keyphrases

hepatitis b virus
liver failure
risk factors
locally advanced
fatty acid
squamous cell carcinoma
radiation therapy
rectal cancer