Effects of Preoperative HbA1c Levels on the Postoperative Outcomes of Coronary Artery Disease Surgical Treatment in Patients with Diabetes Mellitus and Nondiabetic Patients: A Systematic Review and Meta-Analysis.
Jinjing WangXufei LuoXinye JinMeng LvXueqiong LiJingtao DouJing ZengPing AnYaolong ChenKang ChenYi-Ming MuPublished in: Journal of diabetes research (2020)
This meta-analysis showed that higher preoperative HbA1c levels may potentially increase the risk of surgical site infections, renal failure, and myocardial infarction and reduce the length of hospital stay in diabetic subjects after coronary artery disease surgical treatment and increase the risk of mortality and renal failure in nondiabetic patients. However, there was great inconsistency in defining higher preoperative HbA1c levels in the studies included; we still need high-quality RCTs with a sufficiently large sample size to further investigate this issue in the future. This trial is registered with CRD42019121531.
Keyphrases
- coronary artery disease
- end stage renal disease
- patients undergoing
- systematic review
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- cardiovascular events
- heart failure
- peritoneal dialysis
- randomized controlled trial
- healthcare
- percutaneous coronary intervention
- study protocol
- left ventricular
- cardiovascular disease
- glycemic control
- open label
- adverse drug
- acute coronary syndrome
- meta analyses