Protein expression of angiotensin-converting enzyme 2, a SARS-CoV-2-specific receptor, in fetal and placental tissues throughout gestation: new insight for perinatal counseling.
V Faure-BardonP IsnardN RouxM Leruez-VilleT MolinaB BessieresYves VillePublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)
Marked placental expression of ACE2 provides a rationale for vertical transmission at the cellular level. Absence of ACE2 expression in the fetal brain and heart is reassuring regarding the risk of congenital malformation. Clinical follow-up of infected pregnant women and their children is needed to validate these observations. © 2020 International Society of Ultrasound in Obstetrics and Gynecology.
Keyphrases
- angiotensin converting enzyme
- angiotensin ii
- pregnant women
- poor prognosis
- sars cov
- binding protein
- magnetic resonance imaging
- gene expression
- heart failure
- preterm infants
- white matter
- long non coding rna
- atrial fibrillation
- blood brain barrier
- computed tomography
- hiv infected
- coronavirus disease
- hiv testing
- resting state
- men who have sex with men
- pregnancy outcomes
- subarachnoid hemorrhage