Comparison of the Pharmacokinetic Profiles of Trientine Tetrahydrochloride and Trientine Dihydrochloride in Healthy Subjects.

Karl Heinz WeissCatherine ThompsonPeter DogteromYi-Jin ChiouTim MorleyBrinley JacksonNaseem AminCamille Omar Farouk Kamlin

Published in: European journal of drug metabolism and pharmacokinetics (2021)

Compared with an identical dose of a TETA 2HCl formulation, the TETA 4HCl formulation provided more rapid absorption of trientine and greater systemic exposure in healthy subjects. Clinical Trials Number EudraCT # 2015-002199-25.

Keyphrases

clinical trial
drug delivery
loop mediated isothermal amplification
randomized controlled trial
phase iii