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Continuing versus withdrawing ixekizumab treatment in patients with axial spondyloarthritis who achieved remission: efficacy and safety results from a placebo-controlled, randomised withdrawal study (COAST-Y).

Robert B M LandeweLianne S GenslerDenis PoddubnyyProton RahmanMaja HojnikXiaoqi LiSoyi Liu LeageDavid AdamsHilde CarlierFilip E Van den Boschnull null
Published in: Annals of the rheumatic diseases (2021)
Patients with axSpA who continued treatment with IXE were significantly less likely to flare and had significantly delayed time-to-flare compared with patients who withdrew to PBO.
Keyphrases
  • placebo controlled
  • double blind
  • clinical trial
  • study protocol
  • randomized controlled trial
  • disease activity
  • squamous cell carcinoma
  • rheumatoid arthritis
  • ankylosing spondylitis
  • phase ii study