Impact of schizophrenia genetic liability on the association between schizophrenia and physical illness: data-linkage study.

Kimberley M KendallAnn JohnSze Chim LeeElliott ReesAntonio F PardiñasMarcos Del Pozo BanosMichael J OwenMichael C O'DonovanGeorge KirovKeith LloydIan JonesSophie E LeggeJames T R Walters

Published in: BJPsych open (2020)

This study demonstrates the value of and potential for linking genetic data from clinically ascertained research studies to anonymised health records. The increased risk for physical illness in schizophrenia is not caused by genetic liability for the disorder.

Keyphrases

bipolar disorder
genome wide
mental health
physical activity
electronic health record
public health
copy number
big data
gene expression
machine learning
hepatitis c virus
climate change
deep learning
artificial intelligence
antiretroviral therapy
health promotion