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Novel Relaxin Receptor RXFP1 Agonist AZD3427 in the Treatment of Heart Failure: A Phase 1a/b, First-in-Human, Randomized, Single-Blind, Placebo-Controlled Study.

Kathleen ConnollyRichard T GeorgeSami OmarElin MatssonMagnus ÅstrandMagnus AlthageDaniel PettersenEsha MohamedKelly FangJoao Augusto Costa LimaMirjana KujacicHelena ÖdesjöMichelle TurtonPetra JohannessonAnders GabrielsenMarcin Ufnal
Published in: Journal of the American Heart Association (2024)
URL: https://www.clinicaltrials.gov; Unique Identifier: NCT04630067.
Keyphrases
  • heart failure
  • double blind
  • endothelial cells
  • open label
  • clinical trial
  • phase iii
  • left ventricular
  • atrial fibrillation
  • pluripotent stem cells
  • binding protein
  • study protocol
  • replacement therapy