Genetic Variants in the Fat Mass and Obesity-Associated Gene and Risk of Obesity/Overweight in Children and Adolescents: A Systematic Review and Meta-Analysis.

Maryam EghbaliAzadeh MottaghiSara TaghizadehSara Cheraghi

Published in: Endocrinology, diabetes & metabolism (2024)

In this study, we have found that the FTO rs9939609 and rs1421085 are associated to an increased risk of obesity among children and adolescents. Besides, the findings of this study further reaffirmed the established link between rs9939609 and obesity in children and adolescents.

Keyphrases

weight loss
insulin resistance
metabolic syndrome
weight gain
type diabetes
high fat diet induced
adipose tissue
gene expression
fatty acid
transcription factor