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Anticoagulation and Transfusions Management in Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: Assessment of Factors Associated With Transfusion Requirements and Mortality.

Gennaro MartucciGiovanna PanarelloGiovanna OcchipintiVeronica FerrazzaFabio TuzzolinoDiego BellaviaFilippo SanfilippoCristina SantonocitoAlessandro BertaniPatrizio VituloMichele PilatoAntonio Arcadipane
Published in: Journal of intensive care medicine (2017)
Implementation of a comprehensive protocol for anticoagulation and transfusions in VV-ECMO for ARDS resulted in a low PRBC requirement, and an ECMO survival comparable to data in the literature. Lower ATIII emerged as a factor associated with increased need for transfusions. Higher PRBC transfusions were associated with ECMO mortality. Further investigations are needed to better understand the right level of anticoagulation in ECMO, and the factors to take into account in order to manage personalized transfusion practice in this select setting.
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