Anticoagulation and Transfusions Management in Veno-Venous Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome: Assessment of Factors Associated With Transfusion Requirements and Mortality.
Gennaro MartucciGiovanna PanarelloGiovanna OcchipintiVeronica FerrazzaFabio TuzzolinoDiego BellaviaFilippo SanfilippoCristina SantonocitoAlessandro BertaniPatrizio VituloMichele PilatoAntonio ArcadipanePublished in: Journal of intensive care medicine (2017)
Implementation of a comprehensive protocol for anticoagulation and transfusions in VV-ECMO for ARDS resulted in a low PRBC requirement, and an ECMO survival comparable to data in the literature. Lower ATIII emerged as a factor associated with increased need for transfusions. Higher PRBC transfusions were associated with ECMO mortality. Further investigations are needed to better understand the right level of anticoagulation in ECMO, and the factors to take into account in order to manage personalized transfusion practice in this select setting.
Keyphrases
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- atrial fibrillation
- mechanical ventilation
- venous thromboembolism
- respiratory failure
- primary care
- cardiovascular events
- healthcare
- cardiac surgery
- systematic review
- randomized controlled trial
- quality improvement
- sickle cell disease
- cardiovascular disease
- intensive care unit
- deep learning